Synthesis of Ureido-s-triazines

Synthesis and biological activity of substituted 2,4,6-s-triazines.

Reaction of 7-hydroxy-4-methyl coumarin with amido/ imido alcohols in ethanol containing concentrated hydrochloric acid afforded 8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-coumarins (1a-f). Interaction of 1a-f with hydrazine hydrate in pyridine resulted in 1-amino-8-aralkyl amido/imido-alkyl-7-hydroxy-4-methyl-2-oxo-quinolines (2a-f). Treatment of 2 with formaldehyde in ethanol resulted in ...

Biodegradation of Chlorinated s-Triazines

The catabolism of chlorinated s-triazines, e.g., herbicides, is incompletely understood. The first demonstration of their quantitative microbial degradation is the fungal dealkylation of simazine (CEET [for meaning of abbreviations throughout, see Table 1, footnote a]) to two major products, deethylsimazine (CEAT; two-thirds of total) and an unidentified s-triazine (one-third of total) (11, 12)...

Synthesis of 2,4,6-tri-substituted-1,3,5-triazines.

Several specific synthetic protocols were developed for the preparation from cyanuric chloride of a range of symmetric and non-symmetric di- and tri-substituted 1,3,5-triazines containing alkyl, aromatic, hindered, chiral and achiral hydroxyalkyl, ester and imidazole groups via sequential nucleophilic substitution of the C-Cl bond by C-O, C-N and C-S bonds.

s-Triazines as Nitrogen Sources for Bacteria

Isolation of bacteria able to utilize s-triazines as the sole and limiting nitrogen sources for growth is described. Three strains of Pseudomonas (A, D, and F) and two strains of Klebsiella pneumoniae (90 and 99) were examined. Strains D and F utilized N-ethylammelide, N-isopropylammelide, ammeline, ammelide, cyanuric acid, and ammonium ion as nitrogen sources. Strain A utilized melamine, ammel...

Synthesis and antibacterial activity of a novel biphenyl-ureido penicillin.